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Opioid script changes mean well but some left with chronic pain

11 March 2021
We shouldn't use a 'one size fits all' approach
The new regulations on opioid prescriptions certainly have merit, but without providing patient support, it is a one-dimensional strategy to reduce opioid use, writes PhD candidate Aili Langford and co-authors.

Chronic pain affects about聽. Internationally,聽聽of people with chronic non-cancer pain take opioids to manage their condition.

In Australia, opioids are among the most frequently used聽. The most聽聽include codeine, tramadol, oxycodone, morphine, methadone and fentanyl.

In June 2020, the federal government made several changes to regulations that govern the prescription and supply of opioids, significantly impacting people living with chronic pain.

The new regulations certainly have merit, given there鈥檚 been a聽聽from prescription opioid misuse in Australia over recent years.

However, changes to medication regulations alone are a one-dimensional strategy to reduce opioid use. Other strategies are needed to support patients, including better patient education and providing patients with other pain management options.

, published last year, shows a 'one-size-fits-all' approach to reducing opioid use isn鈥檛 favoured by prescribers or patients. Instead, patients should have access to individualised and coordinated care.

The new regulation

Australia鈥檚 drug regulator, the聽, says opioids should only be used for the short-term management of severe pain (for example, after surgery) and only when other pain medicines are not suitable or effective, for example in cases where patients can鈥檛 tolerate non-steroidal anti-inflammatories such as ibuprofen.

The new regulations say opioids should no longer be prescribed for chronic non-cancer pain, except in 鈥溾.

Other changes include reduced opioid pack sizes and fewer repeat prescriptions, meaning patients may need to see their doctor more often for ongoing supplies.

For patients using opioids for a period of 12 months or longer, a second prescriber must assess and approve ongoing opioid supply.

Strong opioids such as morphine and fentanyl can only be used in patients with cancer, in palliative care, or after a trial of lower-strength opioids.

States across Australia are currently in the process of introducing national聽. Health-care professionals who are prescribing or dispensing medicines will be able see a patient鈥檚 prescription history.

Why were the changes made?

Opioid-related deaths increased by聽. Prescription opioids are responsible for more deaths than illicit opioids such as heroin.

Evidence suggests long-term opioid use (greater than three months) for chronic non-cancer pain offers limited benefit. Instead, research suggests聽听补苍诲听聽often improve when opioids are tapered or deprescribed, particularly combined with other treatments such as cognitive and physical therapy. Tapering refers to slowly reducing the amount of the drug taken over time, with the aim of eventually stopping it altogether.

聽regulatory changes were made to reduce the harms of prescription opioids and 鈥渆nsure the safe and effective prescribing and use of opioids while maintaining access for patients who need them鈥.

Many patients are left without options

The full impact of these regulatory changes isn鈥檛 known yet. In clinical practice, it鈥檚 hard for both health-care professionals and patients to accept and respond to these changes.

Although the new rules may reduce harms from prescription opioids, they may make it聽聽to access medicines.

Opioids are often prescribed when patients are unable to use other medicines, or when they鈥檙e not effective.

Other strategies to manage pain, such as seeing a physiotherapist or psychologist, are often expensive and there can be long wait times to see pain specialists.

Reduced access to opioids may mean patients are left without pain management options.

Prescribers can still give opioids to patients with chronic non-cancer pain, if they think the benefits of continuing the medication will outweigh the risks. However, there were initial聽聽on how to implement these changes.

Many researchers have longstanding concerns opioids may be stopped聽聽from patients.

In the United States, abrupt and forced opioid tapering has caused聽. These include increased or uncontrolled pain, acute opioid withdrawal, use of illicit opioids, depression and suicide.

Alternatively, evidence suggests聽聽between health-care professionals and patients may聽听补苍诲听.

If opioids are to be discontinued for certain patients, it must be done safely.

We shouldn鈥檛 use a 鈥榦ne-size-fits-all鈥 approach

Health-care professionals must consider ways in which patients can access appropriate and affordable pain management.

Access to non-opioid pain management can be limited for many people, particularly non-drug treatments such as physiotherapy, psychology or multidisciplinary pain management. Challenges include high out-of-pocket costs, lack of availability particularly in rural and remote locations, and long waiting lists.

With the new regulations, each prescriber will need to make a decision about the harms and benefits of ongoing opioid use for individual patients.

If opioids are to be stopped for a patient,聽聽recommend to聽聽to prevent withdrawal symptoms.

Despite efforts to inform Australian health-care professionals on the聽, many聽聽they need more guidance on how to successfully deprescribe opioids.

There are resources available for both聽听补苍诲听聽to assist with opioid tapering.聽聽on opioid deprescribing are under development and are due to be published in 2022.


This article was first published on .聽It was written by PhD Candidate Aili Langford, Dr Carl Schneider, Professor Christine Lin and Associate Professor Danijela Gnjidic from the School of Pharmacy, Faculty of Medicine and Health at the University of Sydney.聽

Ivy Shih

Media and Public Relations Adviser (Medicine and Health)

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