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Microscope that gets to the heart of matter

12 September 2018
New instrument the first of its kind in Australia
The transmission electron microscope (TEM) can explore matter at the scale of less than 0.06 billionths of a metre helping researchers design materials in renewable energy, medical science, engineering and geosciences.
Professor Julie Cairney using an atom probe at the University of Sydney.

Professor Julie Cairney using an atom probe at the University of Sydney.

Two Nobel Laureates and the NSW Chief Scientist & Engineer have officially unveiled a vital piece of scientific infrastructure at the University of Sydney at a special event on Tuesday, 11 September 2018.

, director of聽, will use the multimillion-dollar microscope to improve the materials used to build life-saving stents that are inserted during heart surgery into patient鈥檚 aortas, saving many Australian lives each year.

鈥淭he work we will do with this machine has the potential to make a huge difference in the world. It will certainly have a transformational effect on my research,鈥 Professor Cairney said.

The (TEM) has the highest resolution of any microscope in Australia. Its addition to the University of Sydney provides researchers with unparalleled access to the mysteries of the atomic structure of materials.

The 4.5-metre tall microscope is housed in the purpose-built $150 million in a room that is shielded from electromagnetic interference and 鈥榝loats鈥 architecturally independent from the building to minimise vibrations.

Speaking at the launch, the Vice-Chancellor and Principal, Dr Michael Spence, said: "This is just one machine in our community but it is really a contribution to scientific discourse across the world. It is through this kind of collaboration that we can meet our global challenges."

He said vision, hard work and collaboration will yield results through the science this instrument can facilitate.

The winner of the for Leadership in Innovation and Science, , said the new machine will be a boon to his ground-breaking research into renewables.

鈥淒efects in functional materials are often critical to performance, be that mechanical, electronic, optical or chemical. The new instrument will allow us to probe active sites, integral for catalysis or energy storage, with atomic clarity,鈥 Professor Maschmeyer said.

Working with Cook Medical Australia, Professor Cairney, from the , is working on new materials that will allow doctors to better see and position the stents during the insertion procedure.

The new microscope will provide essential information about the structure and stability of these materials, allowing her team to be more effective in their work.

Professor Julie Cairney explains how the microscope works to Vice-Chancellor Dr Michael Spence (second from right) and Deputy Vice-Chancellor (Research) Professor Duncan Ivision (right). With them is Dr Magnus Garbrecht, who operates the TEM. Photo by Jayne Ion

Professor Julie Cairney explains how the microscope works to Vice-Chancellor Dr Michael Spence (second from right) and Deputy Vice-Chancellor (Research) Professor Duncan Ivision (right). With them is Dr Magnus Garbrecht, who operates the TEM. Photo Jayne Ion

The TEM is the only such microscope in Australia that is 鈥渕onochromated鈥 and 鈥渄ouble corrected鈥. This means it can simultaneously analyse the atomic structure and the spectral nature of materials.

The resolution of this technique is breathtaking. The machine can obtain images with resolution better than 0.06 billionths of a metre (0.06 nanometres). That is about 10 times smaller than the distance between silicon atoms or five times smaller than the distance between carbon atoms in diamond.

鈥淲ith this device, we not only get to see the atomic structure but simultaneously analyse chemical information, such as inter-atomic forces, which is a huge advantage in materials science. The research application space is truly vast,鈥 Professor Cairney said.

The aberration-corrected transmission electron microscope in the Sydney Nanoscience Hub.

The aberration-corrected transmission electron microscope in the Sydney Nanoscience Hub.

The microscope, which is available for use by industry, has applications in geosciences, mining, chemical and advanced manufacturing industries. It is critical for the design of semiconductor structures such as those fabricated in cleanrooms at the聽聽in the Sydney Nanoscience Hub.

Deputy Vice-Chancellor (Research), Professor Duncan Ivison, said: 鈥淭his launch represents an important advance in Australia鈥檚 national capability in electron microscopy. This is a major milestone in the University鈥檚 research strategy, which places emphasis on world-class, University-wide infrastructure.鈥

The new NSW Chief Scientist & Engineer,聽聽launched the device in his first week of official functions alongside two Nobel Laureates in Chemistry who are visiting Sydney for the聽, which is jointly hosted by the University of Sydney and UNSW.

Columbia University鈥檚聽聽was awarded a聽聽for developing another innovative type of transmission electron microscopy, known as cryo-TEM, which is able to determine biological structures in solution to high resolution. The University of Sydney will soon acquire a cryo-TEM to add to our impressive array of scientific infrastructure.

"I want to emphasise the role of scientific infrastructure," Professor Frank said at the launch. "I've done most of my work computationally - and that data had to come from somewhere from people who can operate these microscopes.

"It is from efforts such as what I see happening here at Sydney where this happens. This really is a milestone for your institution."

Joining Professor Frank was Technion University Israel鈥檚聽. He was awarded the聽聽for the discovery of quasicrystals, a highly unusual and complicated form of matter.

"You have fantastic equipment here," Professor Shechtman said. "But the questions are: where are the problems to solve? Will these wonderful pictures bring you new science? What do they mean for the real questions you want to solve.

"The most important thing is the man or woman behind the science. Developing the human capacity to use these instruments is the important job, almost as important as solving the scientific questions themselves."

Differential phase contrast in scanning transmission electron microscopy mode reveals the electric field vectors around single magnesium atoms acting as dopants in scandium nitride. Image by Magnus Garbrecht

Differential phase contrast in scanning transmission electron microscopy mode reveals the electric field vectors around single magnesium atoms acting as dopants in scandium nitride. Image by Magnus Garbrecht

Marcus Strom

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