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Leading multidisciplinary research in musculoskeletal health
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We bring together a diverse group of world leading researchers, strengthening our ability to achieve transformative research, while delivering new opportunities and greater assistance to our teams.

¸ßÇ帣ÀûƬ strategy will focus on areas of strength, drawing upon the expertise and resources of the University of Sydney, Sydney Local Health District and the Northern Sydney Local Health District.

Our Research Portfolios bring together the tremendous expertise across the flagships’ well-respected research teams. Collectively, they will undertake collaborative research addressing the needs of society and will strive to discover new ways to prevent, manage and cure disabling musculoskeletal conditions, to improve health outcomes for all.

Arthritis, inflammation and autoimmune conditions

We undertake basic/discovery, translational, and clinical research into all forms of arthritis driven by the immune system, ageing, injury, biomechanics, and metabolic disease, including:

  • rheumatoid arthritis,
  • psoriatic arthritis,
  • lupus,
  • ankylosing spondylitis,
  • osteoarthritis, and
  • gout.

Our vision is to define disease mechanisms and pave the way for new and better treatment options, slower disease progression, decreased symptoms and lifestyle impacts, and ideally, potential cures, for these chronic, painful, disabling conditions.

Advisory group

  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýÌý(°ä´Ç-³¦³ó²¹¾±°ù)
  • Associate ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýÌý(°ä´Ç-³¦³ó²¹¾±°ù)Ìý
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • ¶Ù°ùÌý
  • Nicole D’Souza
  • Virginia Gee
  • Ka Martina

Researchers

  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýÌý(°ä´Ç-³¦³ó²¹¾±°ù)
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • Associate ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • Associate ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýÌý(°ä´Ç-³¦³ó²¹¾±°ù)
  • ¶Ù°ùÌý
  • ¶Ù°ùÌý
  • ¶Ù°ùÌýManasi Murthy Mittinty
  • ¶Ù°ùÌý
  • ¶Ù°ùÌý
  • Naomi Simick Behera
  • Marita CrossÌý
  • Nicole D’Souza
  • Virginia GeeÌý
  • Bimbi Gray
  • Laura Hutchison
  • Sascha Karunaratne
  • Sarah Kobayashi
  • Ka Martina
  • Toni MichaelÌý

Back and neck pain

Our focus is on understanding the mechanisms and outcomes of back and neck pain, developing and testing interventions, and working with partners to improve clinical care and patient outcomes.

We're made up of consumers, clinicians, junior and senior researchers, research students and professional staff from a variety of backgrounds including physiotherapy, chiropractic, pharmacy, rheumatology, emergency medicine and orthopaedic surgery

We welcome new members regardless of research experience and academic seniority.

This trial will evaluate the effect of an opioid stewardship intervention on general practitioner prescribing of opioid medicines dispensed to their patients with low back pain over 1 year from index visit.

Lead investigator:Ìý¶Ù°ùÌý

Investigator team:Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýÌý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýFiona Blyth,Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, Associate ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýPatrick Kelly, Associate ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý,Ìý ¶Ù°ùÌýThomas Lung, ¶Ù°ùÌý, Professor Louisa Degenhardt, Associate Professor Rowena Ivers

Operational team:ÌýMr Daniel Chapman, Miss Lisa Vizza

This trial will evaluate the effect of introducing a coordinated support system (linking hospital outpatient physiotherapy services to a public health coaching service) at discharge from low back pain treatment, compared with usual care provided at discharge.Ìý

Lead investigator:Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý

Investigator team:ÌýEmeritus ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýAdrian Bauman,Ìý ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, Associate ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýÌý¶Ù°ùÌý,Ìý¶Ù°ùÌýEmma Ho, Professor Paul Hodges, Professor Chris Lonsdale, Dr Dragana Ceprnja, Dr Ornella Clavisi,ÌýDr Alice Kongsted,ÌýDr Qiang Li,ÌýDr Kate Reid,ÌýMr Mark Halliday,ÌýMr Matthew Jennings,ÌýMs Katherine Maka,ÌýMs Tahlia Reynolds

Operational team:ÌýDr Carlos Mesa Castrillon,Ìý¶Ù°ùÌýEmma Ho, Mr Julian Comis, Ms Kate Roberts,ÌýMr James Zouch

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HELP will investigate whether a media-led intervention presenting evidence-based back pain management information in General Practice waiting rooms is effective at changing patient beliefs and medical practitioner behaviours (prescriptions and referrals).

Lead investigator:Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý

Investigator team:ÌýEmeritus ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýAdrian Bauman, ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, ¶Ù°ùÌý, ¶Ù°ùÌý,Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ù Andrew Georgiou

Operational team:ÌýMs Carolina G. Fritsch, Mr Michael Knox, Ms Alessandra Marcelo, Mr Riyaas Mohammed, Ms Joanna Prior

NUDG-ED is a 2x2 factorial, open label, before-after, cluster randomised controlled trial that will investigate behavioural ‘nudging’ strategies to reduce use of low value care for low back pain in ED.Ìý

Lead investigator:ÌýDr Adrian Traeger

Investigator team:Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýÌý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý,Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ù Rachelle Buchbinder,Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ù Louise Cullen, Professor Ian Harris, Professor Jeff Linder, Professor Enrico Coiera, Mr Qiang Li

Operational team:ÌýDr Swee Sharma, Ms Gemma Altinger

Find out more information about the trial.

The Oral Steroids In Sciatica (OASIS) trial is a randomised, placebo-controlled, double-blind trial that will evaluate a tapering regimen of oral prednisolone in 200 participants with acute sciatica.

Lead investigator:Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý

Investigator team:Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý,Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, ¶Ù°ùÌý, ¶Ù°ùÌýChristina Abdel Shaheed, Professor Rachelle Buchbinder, Professor Ric Day, Professor Jane Latimer, Dr Qiang Li, Dr Chang Liu, Dr Bethan Richards

Operational team:ÌýMs Melanie Hamilton, Mrs Hanan McLachlan, Ms Melissa Webb

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OPAL is a randomised, placebo-controlled, triple-blinded trial that investigates the judicious use of an opioid analgesic in 346 participants with acute low back pain and/or neck pain.Ìý

Lead investigator:Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý

Investigator team:Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý,Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýLaurent Billot,Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ù Ric Day, Professor Bart Koes,Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ù Jane Latimer,ÌýDr Caitlin Jones

Operational team:ÌýMs Melanie Hamilton, Mrs Hanan McLachlan, Ms Melissa Webb

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SUcceSS is a prospectively registered, randomised placebo-controlled trial of decompressive spinal surgery in people with symptomatic lumbar spinal stenosis.Ìý

Lead investigator:Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý

Investigator team:Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ù Jane Latimer, ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý,Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ù David Beard,Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ù Rachelle Buchbinder, Professor Ian Harris,Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ù Stephen Jan,ÌýDr Gavin Davis,ÌýDr Qian Li,ÌýDr Ralph Mobbs,ÌýDr Ralph Stanford

Operational team:Ìý¶Ù°ùÌýEmma Ho, Mr Michael Knox, Ms Joanna Prior

Find out more information about the trial.

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RESHAPED will develop, implement, and evaluate a novel model of care for the management of low back pain in emergency departments (ED). The model of care aims to relieve pressure on EDs.Ìý

Lead investigator:Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ù

Investigator team:Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý,Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý,Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, Associate ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, ¶Ù°ùÌýÌý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ù Laurent Billot,Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ù Rachelle Buchbinder, Professor Ian Harris, Professor Leigh Kinsman,Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ù Jonathan Wiggers, Dr James Edwards, Dr Narcyz Ghinea,ÌýDr Eileen Rogan

Operational team:ÌýDr Danielle CoombsÌý

TEXT4myBACK is a randomised clinical trial assessing the efficacy and cost effectiveness of a semi-personalised text message intervention for people with acute low back pain.Ìý

Lead investigator:Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý

Investigator team:Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý,Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, Ms Carolina G. Fritsch, Ms Joanna Prior

Operational team:ÌýMs Carolina G. Fritsch, Ms Alessandra Marcelo, Ms Joanna Prior

.Ìý

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This trial will evaluate the effectiveness and feasibility of implementing ‘Back@Home’, a virtual hospital model of care for patients with musculoskeletal low back pain presenting to the emergency department, in reducing length of hospital stay.

Lead investigator:Ìý¶Ù°ùÌý

Investigator team:Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý,ÌýDr Danielle M Coombs, ¶Ù°ùÌýThomas Lung,ÌýMsÌýAlla Melman, MrÌýMin Jiat Teng,Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ù Laurent Billot,ÌýDr Owen Hutchings, Dr Qiang Li, Dr Mona Marabani, Dr Eileen Rogan

Empower is a randomised controlled trial of an eHealth-supported intervention comprised of a physical activity plan and progressive resistance exercise program for people living in rural Australia with chronic non-specific low back pain and/or knee osteoarthritis compared to usual care.

Lead investigator:Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý

Investigator team:ÌýEmeritus ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýAdrian Bauman, ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, Associate ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, Associate ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýÌýDr Carlos Mesa Castrillon, Mr Phillip R Davis,ÌýMr Antonio Michell de Gregorio, Professor Kim Bennell,ÌýDr Grahame Knox,ÌýDr Ornella Clavisi, ¶Ù°ùÌýStephen Bunker,ÌýMs Kristy Hatswell

Operational team:ÌýDr Carlos Mesa Castrillon,ÌýMr Antonio Michell de Gregorio

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NHMRC Fellows

Several theme members hold externally funded fellowships:

  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý: NHMRC Leadership Fellow 1
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý: NHMRC Leadership Fellow 3
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý:ÌýNHMRC Emerging Leadership Fellow 2
  • ¶Ù°ùÌý: NHMRC Emerging Leadership Fellow 1
  • ¶Ù°ùÌý:ÌýNHMRC Emerging Leadership Fellow 1

They are all happy to help other members prepare a competitive application.

Advisory group

  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýÌý(°ä´Ç-°ä³ó²¹¾±°ù)
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýÌý(°ä´Ç-°ä³ó²¹¾±°ù)
  • Dr Danielle Coombs
  • ¶Ù°ùÌýEmma Ho
  • ¶Ù°ùÌý

Researchers

  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • Dr Adrian Traeger
  • ¶Ù°ùÌýDavid Anderson
  • ¶Ù°ùÌýNathalia Costa
  • ¶Ù°ùÌý
  • Dr Caitlin Jones
  • ¶Ù°ùÌýChristina Abdel Shaheed
  • ¶Ù°ùÌý
  • ¶Ù°ùÌý
  • ¶Ù°ùÌý
  • ¶Ù°ùÌý
  • Ana Paula Carvalho-e-Silva
  • Carlos Ivan Mesa Castrillon
  • Sonia Coates
  • Josielli Comachio
  • Alex GriffinÌý
  • Mr Christopher Han
  • Meiyi Huo
  • Alla Melman
  • Simon Olivotto
  • Kate Roberts
  • Danielle Stone
  • Simon Vella
  • James Zouch

Healthy ageing, physical activity and rehabilitation

The musculoskeletal system is critical to healthy ageing, physical activity and the rehabilitation of people following injury and disease.

We focus on the prognosis, treatment and prevention of musculoskeletal problems that impede healthy ageing, physical activity and rehabilitation.

We conduct qualitative and quantitative research with an emphasis on translating research findings into practice and public health initiatives.

We hope the findings of this project lead to the development of home-based exercise programs to improve strength, balance and reduce falls and improve shoulder functioning in older people.

The aim of this project is to compare the effectiveness of two home-based exercise programs – one aimed at improving lower limb strength and balance for preventing falls and the other aimed at improving upper limb strength and mobility to reduce shoulder dysfunction.

Participants are taught the exercises in a group workshop setting and then complete their exercises at home three times each week for 12 months.

Participants are provided with a calendar to record their exercises and falls each month, and a program manual and exercise weights.

This project is no longer recruiting.

Lead investigator:Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý

Investigator team:Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, Professor EmeritusÌýAdrian Bauman, Associate ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýKaren Ginn,ÌýDr Paul Van Den Dolder,ÌýDr Susan Furber

For more information about this project, please contact ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý.

This project has received ethics approval from the University of Wollongong and Illawarra Shoalhaven Local Health District.

This is a NHMRC Partnership Grant (2014–2019).

We hope the findings of this project lead to increased physical activity,Ìýdecreased risk of falling and improved eating habits in older people.

The aim is to evaluate the effectiveness of two 12 monthÌýhealthy ageing strategies among people who attend established, community-based groups.

The first intervention is a physical activity and fall prevention intervention, including telephone-based health coaching and written information on physical activity and falls.

The second is a nutrition intervention involving telephone-based health coaching and written information about eating habits.

The trial also aims to establish the impact of these interventions on physical activity, eating habits, weight (body mass index), goal attainment, mobility confidence, quality of life, fear of falling, risk-taking behaviour, well-being, and mood.

This project is no longer recruiting.

Lead investigator:Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý

Investigator team:Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý,Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ù Dafna Merom,Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ù Chris Rissel, Professor Stuart Smith,ÌýAssociate Professor Allison Tong

For more information about this project, please contact ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý.

This project has received ethics approval from the University of Sydney Human Research Ethics Committee.

This is a NHMRC Project Grant (2015–2018).

We hope the findings of this project lead to the development of a yoga-based exercise program to prevent falls in people aged 65 and over.

The aim of this project is to assess the effectiveness of a 40 weekÌýyoga program, compared with an advice booklet, on falls.Ìý

We will also assess the effectiveness of the program on other key indicators of healthy ageing, such as mental health, establish the cost-effectiveness of the intervention, and measure the yoga program’s potential for implementation.

Participants allocated to the yoga-based exercise group will attend 40 weeks of twice-weekly, one-hour yoga classes in established yoga studios in Sydney with experienced yoga teachers.

Participants will be asked to complete a home-based yoga program for at least two extra 20-minute sessions each week.

For more information about this project, please contact us at:Ìýsph.sagetrial@sydney.edu.au

Lead investigator:Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý

Investigator team:Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, Professor Stephen Lord,Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý,Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ù EmeritusÌýAdrian Bauman,Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ù Chris Rissel, Emeritus ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý,Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ù Roberta Shepherd, Associate ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýPatrick Kelly,Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ù Kaarin Anstey,ÌýDr Anne Grunseit, Romina Sesto

This project has received ethics approval.

The sponsor of this trial is the University of Sydney.

Funding is from the National Health and Medical Research Council.

The aim of this trial is to assess the effectiveness of the Ironbark fall prevention program on reducing the number of falls in Aboriginal and Torres Strait Islander people who are 45 years and older.

This group is compared to control participants who receive a healthy ageing program.

The Ironbark program includes interactive discussion about fall risk factors, combined with balance and strength training.

It was created after a successful New South Wales pilot and will now run across New South Wales, South Australia and Western Australia.

This study is not yet recruiting participants.

Lead investigator:Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ù Rebecca Ivers

Investigator team:Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý,Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý

For more information on this George Institute for Global Health trial, please contactÌýjcoombes@georgeinstitute.org.au.Ìý

This study is funded through the NHMRC.

We hope the findings of this project lead to enhanced promotion of physical activity by health professionals for people aged 50+ and people of all ages with a physical disability.

The aim of the project is to toÌýcollaboratively develop and test a strategy to support health professionals to promote PA to their patients – including older adults and children/adolescents/adults with physical disabilities – within their daily clinical practice.

The project is currently recruiting participants for phase one of the study-collaborative implementation strategy development.

In this phase we will conduct interviews, focus groups, workshops and surveys with health professionals, exercise providers and consumers to identify barriers to PA promotion and collaboratively develop the evidence-based implementation strategies and intervention elements.

Phase 2 of the study is a Type 2 hybrid effectiveness-implementation cluster randomised trial (2023 onwards).

In Phase 2 we will test the effectiveness of the implementation strategies and intervention elements in a Type 2 hybrid cluster randomised trial recruiting 800 participants across 30 sites.

Lead investigator:Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý

Investigator team:ÌýOur team comprises of academics, public health experts and health economists from the University of Sydney, UNSW, Western Sydney University and Australian Catholic University, as well as multi-disciplinary clinicians from five Local Health Districts (Sydney, Western Sydney, South-Western Sydney, South-Eastern Sydney and Sydney Children Hospitals Network). Partner organisations include Disability Sport Australia, Australian Physiotherapy Association, Clinical Excellence Commission, iCare and Belgravia Leisure.

For more information about this project, please contactÌýKate Purcell.

This project has received ethics approval from Local Health District Ethics Committees and is being funded by an NHMRC Partnership Grant.

We hope the findings of this project lead to improved physical activity levels in adults who have difficulty walking.

The aim is to evaluate the effectiveness of two physical activity interventions on adults with self-reported walking difficulty.

The participant will be allocated to one of three groups.

The first intervention includes: a tailored physical activity plan based on a face-to-face assessment with a physiotherapist; six months of phone-based health coaching; use of technology to keep you active and access to online resources.

The second intervention is a less intensive health-coaching program involving a phone consultation with a physiotherapist, monthly text messages to follow up and access to online resources.

The third group will receive no intervention for the first six months and then receive the second intervention for the second six months.

The project will be conducted over 12 months.

This project is no longer recruiting.

Lead investigator:Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý

Investigator team:Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý,ÌýAssociate ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý,Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ù Rana Hinman, Professor Maria Crotty, Professor Tammy Hoffmann, Professor Nicholas Taylor

For more information about this project, please contact Associate ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý.

This is a NHMRC Project Grant (2018–2021).

We hope the findings of this project will lead to improved physical activity levels in patients receiving brief physical activity counselling as part of their physiotherapy treatment.

BEHAVIOUR is a hybrid type II cluster randomised controlled trial.

The aim is to evaluate the effectiveness of a multi-faceted implementation strategy compared to usual care on increasing the proportion of patients receiving brief physical activity counselling as part of hospital-based physiotherapy care, and subsequently improving the physical activity levels among these patients.

Physiotherapists in the intervention group will be assigned to receive the multi-faceted implementation strategy immediately to support them to incorporate brief physical activity counselling into their routine care.

The main implementation strategies will include education training, creating a learning collaborative, tailored strategies to address community referral barriers, facilitation and audit and feedback.

The control group will receive an updated version of the implementation strategy at the end of the trial.

The trial will be conducted with physiotherapists across all hospitals in South WesternÌýSydney Local Health District and will include participants from culturally and linguistically diverse backgrounds.

Lead investigator:ÌýAssociate ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý

Investigator team:Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, ¶Ù°ùÌý, ¶Ù°ùÌý, Professor Colin Greaves, Dr Bernadette Brady, Dr Lauren Christie, Matthew Jennings,ÌýBalwinder Sidhu

This study is funded through the MRFF preventive & public health grant (2020–2023) and NHMRC TRIP Fellowship (2019–2020).

We hope the findings of this project will lead to improved physical activity levels in people living with moderate to severe traumatic brain injury (TBI).

The aim of this project is to develop clinical practice guidelines for physical activity in people across all ages living with moderate-to-severe traumatic brain injury (TBI) in Australia.

A plan will also be developed for the effective implementation of these guidelines.

The first stage involves evaluating the fit of the 2020 WHO physical activity and sedentary behaviour guidelines for people living with disability to those living with a moderate-to-severe TBI.

This includes considering the evidence available regarding physical activity in TBI, preferences for physical activity, perspectives of relevant stakeholders and the feasibility of guideline implementation.

Stage two involves auditing brain injury rehabilitation services across Australia to understand how physical activity is delivered and promoted to identify current practice and where practice inconsistencies exist.

The third stage involves adapting the WHO guidelines into national clinical practice guidelines for people living with TBI, informed from stages one and two.

The final stage involves the development of a plan for implementation of these national practice guidelines based on the identification of barriers and facilitators.

Lead investigator:ÌýAssociate ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý

Investigator team:Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý,Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ù EmeritusÌýAdrian Bauman, Associate ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, ¶Ù°ùÌý,Ìý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ù Gavin Williams, Associate Professor Sean Tweedy, Professor Luke Wolfenden, Professor Maria Crotty, Associate Professor Adam Scheinberg, Gabrielle Vassallo Nick Rushworth

Collaborating Organisations:ÌýBrain Injury Australia, Connectivity TBI; icareÌýNSW; Heads Together for ABI

Research team:ÌýSakina Chagpar,Ìý,ÌýDr Liam Johnson

This study is funded through theÌýMRFF 2020 Traumatic Brain Injury Mission, Stream 2-incubator (2021–2023).

Advisory group

  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýÌý(°ä´Ç-°ä³ó²¹¾±°ù)
  • Associate ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýÌý(°ä´Ç-°ä³ó²¹¾±°ù)
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý

Researchers

  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýÌý(³¦³ó²¹¾±°ù)
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • Associate ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýÌý(³¦³ó²¹¾±°ù)
  • ¶Ù°ùÌý
  • ¶Ù°ùÌý
  • ¶Ù°ùÌý
  • ¶Ù°ùÌýEmma Ho
  • ¶Ù°ùÌý
  • ¶Ù°ùÌý
  • Ghazi AlnajdiÌý
  • Naomi Simick BeheraÌý
  • Josielli ComachioÌý
  • Rik Dawson
  • Meaghan Harris
  • Jennifer Kent
  • Wing S Kwok
  • Ima Strkljevic
  • Geraldine Wallbank
  • Taylor Wileman

Resources founded by members of this portfolio

Musculoskeletal health in children and adolescents

¸ßÇ帣ÀûƬ focuses on understanding the pathology and mechanisms of these conditions, characterising the clinical outcomes and needs related to these conditions and developing new treatments, services and management strategies to address these needs.

Our activities are underpinned by the principle of person-centredness and focused on outputs that impact the health of young people.

Some of the research programs currently explored by our investigators in this area include:

  • Improving diagnosis and management of children and adolescents with rare genetic disorders affecting skeletal development (Andreas Zankl)
  • Improving the understanding and management of musculoskeletal pain in children and adolescents in primary care and the community (Steve Kamper)
  • Optimising the design and delivery of a digital ankle-foot orthosis workflow for children (Tegan Cheng)

Advisory group

  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, Co-Chair
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý, Co-Chair
  • ¶Ù°ùÌý

Researchers

  • ¶Ù°ùÌý
  • ¶Ù°ùÌý
  • ¶Ù°ùÌý
  • ¶Ù°ùÌý
  • Meaghan Harris

Clinical research, health services and population health research

¸ßÇ帣ÀûƬ encompasses the clinical, health services and population health research that is happening across the Flagship’s condition-specific research themes.

Our focus is on supporting the conduct of research to the highest standard, and to provide a network for those who are interested in this type of research.

Examples of the diverse research methodologies relevant to our theme include clinical trials, observational studies, health economic research and analysis of large datasets using data linkage and/or administrative datasets.

NHMRC Fellows

Several theme members hold externally funded fellowships, including:

  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýÌý(NHMRC Emerging Leadership Fellow 2),Ìý
  • Associate ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýÌý(NHMRC Emerging Leadership Fellow),Ìý
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýÌý2 (Leadership Fellow 2),

and/or hold competitive NHMRC/MRFF grants, including

  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý,Ìý
  • ¶Ù°ùÌýChristina Abdel Shaheed,Ìý
  • Associate ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýFiona Blyth

Advisory group

  • ¶Ù°ùÌýChristina Abdel-ShaheedÌý(°ä´Ç-³¦³ó²¹¾±°ù)
  • ¶Ù°ùÌý
  • Dr Xiaoqian LiuÌý
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýÌý(°ä´Ç-³¦³ó²¹¾±°ù)Ìý
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýFiona BlythÌý
  • Associate ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýSean O’Neil
  • Simon Vella

Researchers

  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýÌý(°ä´Ç-³¦³ó²¹¾±°ù)Ìý
  • ¶Ù°ùÌýChristina Abdel-ShaheedÌý(°ä´Ç-³¦³ó²¹¾±°ù)
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýFiona Blythe
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • Associate ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • AssociateÌý±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ù Sean O’Neill
  • ¶Ù°ùÌý
  • ¶Ù°ùÌýYuan Chair
  • ¶Ù°ùÌý
  • ¶Ù°ùÌý
  • Dr Xingzhong (Jason) Jin
  • Dr Xiaoqian Liu
  • ¶Ù°ùÌý
  • ¶Ù°ùÌý
  • ¶Ù°ùÌý
  • Sonia Coates
  • Marita Cross
  • Kawngil Kang
  • Qianwen Lan
  • Simon Olivotto
  • James Puterflam
  • Min Jiat Teng
  • Simon Vella
  • James Zouch

Discovery research

We're conducting research to understand:

  • the fundamental genetic, molecular, cellular and tissue biological and mechanical processes that are critical to normal development, growth and function of musculoskeletal tissues and organs,Ìý
  • how they adapt in altered conditions (e.g. exercise, ageing, injury, surgery), andÌý
  • how they change in and drive structural and symptomatic disease.Ìý

Our vision is to define key processes, pathways and mechanisms that may be targeted to maintain or improve musculooskeletal health, and prevent, treat and one day cure the chronic, painful, disabling musculoskeletal diseases.

Advisory group

  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýÌý(°ä´Ç-³¦³ó²¹¾±°ù)
  • Associate ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýÌý(°ä´Ç-³¦³ó²¹¾±°ù)
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý

Researchers

  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • Associate ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • ¶Ù°ùÌý
  • Jonathan KoÌý
  • Ima StrkljevicÌý
  • Marita Cross

Digital health and virtual care

We aim to investigate the use of digital technologies to improve the quality and delivery of healthcare services.

The broad scope of our work includes innovative practices such as mobile health, health information technology, wearable devices, telehealth and virtual care.

Advisory group

  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýÌý(°ä´Ç-³¦³ó²¹¾±°ù)
  • ¶Ù°ùÌýÌý(°ä´Ç-³¦³ó²¹¾±°ù)Ìý
  • Min Jiat TengÌý(°ä´Ç-³¦³ó²¹¾±°ù)

Researchers

  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýÌý(°ä´Ç-³¦³ó²¹¾±°ù)
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • ¶Ù°ùÌýDavid Anderson
  • ¶Ù°ùÌýEmma Ho
  • Dr Gustavo Machado (Co-chair)
  • ¶Ù°ùÌý
  • ¶Ù°ùÌý
  • ¶Ù°ùÌý
  • ¶Ù°ùÌý
  • ¶Ù°ùÌý
  • Alla Melman
  • Ana Paula Carvalho-e-Silva
  • Carlos Ivan Mesa Castrillon
  • James Puterflam
  • Josielli Comachio
  • Min Jiat TengÌý(°ä´Ç-³¦³ó²¹¾±°ù)
  • Rik Dawson
  • Xingzhong (Jason) Jin
  • Ye Tian
  • Yuan Chai

Translation research and value in healthcare

¸ßÇ帣ÀûƬ includes projects from any of the Flagship research groups that sit along the translational pipeline from basic sciences research to population health research, with an explicit focus on immediate or future implementation into healthcare policy or practice.

It particularly focuses on:

  • implementation science projects (the study of methods to promote the integration of research findings and evidence into healthcare policy and practice), andÌý
  • the implementation of high-value care (care that is effective and cost efficient and improves health outcomes and experiences that matter to patients, clinicians and health services) and de-implementation of low-value care.

Advisory group

  • Associate ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýÌý(°ä´Ç-³¦³ó²¹¾±°ù)Ìý
  • ¶Ù°ùÌýÌý(°ä´Ç-³¦³ó²¹¾±°ù)Ìý
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý

Researchers

  • Associate ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌýÌý(°ä´Ç-³¦³ó²¹¾±°ù)Ìý
  • ¶Ù°ùÌýÌý(°ä´Ç-³¦³ó²¹¾±°ù)Ìý
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • Associate ±Ê°ù´Ç´Ú±ð²õ²õ´Ç°ùÌý
  • ¶Ù°ùÌý
  • ¶Ù°ùÌýNathalia Costa
  • ¶Ù°ùÌý
  • ¶Ù°ùÌý
  • ¶Ù°ùÌý
  • ¶Ù°ùÌý
  • ¶Ù°ùÌý
  • ¶Ù°ùÌý
  • Naomi Simick BeheraÌý
  • Bimbi GrayÌý
  • Alex GriffinÌý
  • Christopher Han
  • Xingzhong JinÌý
  • Jonathan KoÌý
  • Toni MichaelÌý
  • Simon Olivotto
  • Andrew RobertÌý
  • Min Jiat TengÌý

Initiatives to enable research and research translation

°Õ³ó±ðÌýÌýis a national musculoskeletal and autoimmune biobanking network with state-of-the-art data collection, data linkage, big data analytics and machine-learning capabilities.

°Õ³ó±ðÌýÌýis a free database of over 55,000 trials, reviews and guidelines evaluating physiotherapy interventions.

PEDro also has monthly emails known as Evidence in Your Inbox thatÌý.

They are designed to inform you of the latest research included on PEDro across 15 areas of physiotherapy practice.

°Õ³ó±ðÌýÌýis produced by the PEDro partnership.

It is a free database that indexes primary studies of diagnostic test accuracy and systematic reviews of diagnostic test accuracy studies related to physiotherapy practice.

DiTA also has a monthly Evidence in Your Inbox email thatÌý.

Participate in our research

By working collaboratively with clinicians, researchers, consumers and policy makers, we strive to improve care and health outcomes for people with musculoskeletal conditions.

We are currently recruiting participants for a number of trials across our Centre.

Please check the eligibility conditions carefully before applying for a trial. If you are ineligible for any of our current trials, please check back as this section is updated periodically.

  • Ìý
    ARAD collects information about your arthritis and health, the medications you take, your quality of life, and information from state and federal health registries.

  • A study to reduce the burden of low back pain.
  • Pain and function associated with a pronated foot posture
    This study aims to improve our understanding of why some people with flat/pronated feet are more at risk of foot and lower limb pain.
  • The PROPOSE (Professional Referral to Physical Activity, Sport and Exercise) study is looking to interview people aged 50+ across Australia who have seen a physiotherapist in the past two years. Interviews will take approximately 30 minutes and will be conducted by phone or video call.

  • SUcceSS
    SUcceSS is the world’s first randomised placebo-controlled study of decompression surgery for lumbar canal stenosis.

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