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The biological approach involves finding and then controlling how tumours proliferate.  Researchers know there are specific mechanisms involved, but they are poorly understood. We support an academic chair for the Professor of Melanoma Biology, currently Professor Peter Hersey.

The Professor of Melanoma Biology heads a team of research staff seeking a breakthrough via molecular biology. They conduct a broad range of biological research programs, including:

• carrying out laboratory studies on the molecular biology of melanoma related to the causation, diagnosis, progression and treatment of melanoma.
• investigating the role of immune responses in the initiation and progression of melanoma.
• undertaking translational research, in association with the Professor of Melanoma Oncology, in human melanoma to improve results from existing treatments, to develop new treatments, and to assist in the conduct of industry-sponsored and investigator-driven clinical trials in melanoma. 

The clinical approach is based on detecting and removing all melanoma cells at the earliest possible time. We support an academic chair for the Professor of Melanoma Oncology, currently Professor John Thompson.

The Professor of Melanoma Biology leads and supervises a team of researchers and academics. This team conducts local and international trials of new therapies, new systems of patient management and programs to assess adequately the outcomes of melanoma therapy.