We turn pioneering research into real-world impact. Our diverse portfolio of innovations is ready for licensing, collaboration, and investment—spanning diagnostics, therapeutics, biomedical devices, optical technologies and more.
| Summary | A novel peptide-based technology disrupts immune complexes to prevent life-threatening blood clots caused by Heparin-induced thrombocytopenia (HIT), vaccine-induced thrombotic thrombocytopenia (VITT), and VITT-like diseases. All are severe immune reactions that cause catastrophic blood clots.ÌýÌý |
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| Inventors | Freda Passam, Xuyu Liu, Jose Sail Perdomo |
| Contact | emma-louise.hunsley@sydney.edu.au |
| Summary | An antibody targeting Myc, with the potential to disrupt this otherwise "undruggable" target in various cancers. |
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| Inventors | Dr Mahdi Zeraati, Prof Marcel Dinger |
| Contact | karmen.kong@sydney.edu.au |
| Summary | A small device designed to mimic the appearance of hair, capable of interfacing with the brain for sensing, actuation, and as a delivery mechanism. |
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| Inventors | Omid Kavehei |
| Contact | emma-louise.hunsley@sydney.edu.au |
| Summary | A number of novel transcription factors associated with functional CAR-T cell phenotypes and proliferation, and methods of identifying more. |
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| Inventors | Salvatore Fiorenza, Cameron Turtle |
| Contact | emma-louise.hunsley@sydney.edu.au |
| Summary | This invention is a new copper-sensing molecular probe with applications for early diagnosis of Parkinson’s disease and management of amyotrophic lateral sclerosis. |
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| Inventors | Professor Elizabeth New, Professor Kay Double, Marcus Graziotto, Dr Liam Adair |
| Contact | julius.juarez@sydney.edu.au |
| Summary | This invention is an anti-venom treatment offering a broad-spectrum solution for neutralising toxins from various sources including snakes and marine life. |
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| Inventors | Professor Gregory Neely, Felicity Shu Yin Chung, Nicholas Casewell, Tian Du |
| Contact | emma-louise.hunsley@sydney.edu.au |
| Summary | This invention is a protein-based bioglue formulated to bind to neuronal tissues. |
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| Inventors | Dr Jingjing You, Jiawen Fan, Professor Matthew Simunovic, Professor Gerard Sutton, Dr Sheng Hua |
| Contact | julius.juarez@sydney.edu.au |
| Summary | AÌýmodified silica nanoparticle compositionÌýfor bone regeneration. |
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| Inventors | Chun Xu, Chang Lei, Chengzhong Yu |
| Contact | karmen.kong@sydney.edu.au |
| Summary | Multispectral analysis of urinary biomarkers to non-invasively identify acute tubular necrosis, graft rejection, and non-rejection associated interstitial fibrosis and tubular atrophy. |
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| Inventors | Sonia Saad, Caroll Pollock, Ewa Goldys, Hon Lin Henry Wu, Yandong Lang |
| Contact | emma-louise.hunsley@sydney.edu.au |
| Summary | A series of new ligands that exhibit significantly higher affinity for a biomarker of neuroinflammation. |
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| Inventors | Dr Jonathan Danon, Professor Michael Kassiou, Greta Sohler, Dr Renee Sokias, Dr Tristan Reekie, Dr Eryn Werry |
| Contact | julius.juarez@sydney.edu.au |
| Summary | A novel software to increase CT image quality thereby improving accuracy and decreasing patient radiation dose. |
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| Inventors | Natasha Morton, Ricky Thomas O'Brien, Paul Keall, Jeffrey Barber, Jonathan Sykes, John Kipritidis |
| Contact | emma-louise.hunsley@sydney.edu.au |
| Summary | Plasma treatment to enable cell growth within a microfluidic device for greater accuracy. |
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| Inventors | Marcela Bilek, Jasneil Singh, Anna Waterhouse, Deepu Ashok, Shouyuan Jiang |
| Contact | emma-louise.hunsley@sydney.edu.au |
| Summary | This invention relates to new phage-drug nanoconjugates for combating bacterial infections. |
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| Inventors | Professor Jonathan Iredell, Dr Hien Thi Duong, Huiping Huang |
| Contact | julius.juarez@sydney.edu.au |
| Summary | A novel software capable of predicting 3D lung motion with only 10 x-ray projections, for large scale lung disease screening. |
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| Inventors | Paul Keall, Hunor Kertesz, Owen Dillon, Hilary Byrne, Ricky O'Brien |
| Contact | emma-louise.hunsley@sydney.edu.au |
| Summary | A molecular diagnostic solution with over 95% specificity, leveraging DNA sequencing to objectively differentiate melanoma from benign naevi, thereby reducing the subjectivity and variability of traditional histopathology. |
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| Inventors | Richard A. Scolyer, Georgina Long, Ismael A. V. Correa, Andrew Colebatch, James Wilmott |
| Contact | taylor.syme@sydney.edu.au |
| Summary | AÌýsmall molecule that reduces cholesterol accumulation in Neimann Pick Type C patient cells.Ìý |
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| Inventors | Associate Professor Thomas Grewal, Professor David Hibbs, Professor Paul Groundwater, Associate Professor Andrew Hoy, Dr Eric Sparkes, Dr Jonathan Du,ÌýMsÌýMai K.L. Nguyen.Ìý |
| Contact | emma-louise.hunsley@sydney.edu.au |
| Summary | A novel phage extracellular vesicle (EV) conjugate designed to promote tissue repair in individuals with bacterial infections. |
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| Inventors | Professor Wojciech Chrzanowski, Dr Hien Thi Duong |
| Contact | julius.juarez@sydney.edu.au |
| Summary | This invention relates to peptide mimetic compounds, inspired by the natural healing capabilities of PDGF but engineered to circumvent the pitfalls of prolonged exposure that can lead to fibrosis. |
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| Inventors | A/Professor James Chong, Emily McKinna, Professor Richard James Payne, Daniel Ford, Richard Harvey, Dr Osvaldo Contreras |
| Contact | julius.juarez@sydney.edu.au |
| Summary | An instrumented spinal tool that uses intraoperative measurements and a reference database to guideÌýoptimalÌýspinal cage sizing. |
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| Inventors | Ahmed Mounir Boudali, Elizabeth Clarke, TahaÌýShakoh, YH Yau, Bill Walter |
| Contact | karmen.kong@sydney.edu.au |
| Summary | A PSA-activated peptide sequence for prodrugs that enables targeted therapy for prostate cancer. A new approach for precision therapy for prostate cancer. |
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| Inventors | Trevor Hambley, Elisabeth Tondl |
| Contact | emma-louise.hunsley@sydney.edu.au |
| Summary | A novel software capable of tracking the movement of multiple targets during radiation therapy. |
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| Inventors | Emily Hewson, Paul Keall, Owen Thomas Dillon, Jeremy Booth |
| Contact | emma-louise.hunsley@sydney.edu.au |
| Summary | A targeted TNBC (Triple Negative Breast Cancer) therapy with increased selectivity and efficacy and decreased toxicity. |
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| Inventors | Pegah Varamini, Sepideh Khazeni |
| Contact | julius.juarez@sydney.edu.au |
| Summary | This invention is a new image reconstruction method for new generation linear accelerators that use rapid CBCT acquisition protocols. |
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| Inventors | Dr Mark Gardner, Dr Owen Thomas Dillon, Professor Paul Keall, Dr Hilary Byrne |
| Contact | emma-louise.hunsley@sydney.edu.au |
| Summary | Fibre sensors made of this low YM material will improve existing uses of OFS technology and open new opportunities in smart textiles, wearables, implantable therapeutic devices, healthcare, and soft robotics. |
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| Inventors | Professor Simon Fleming, Dr Richard Lwin, Dr Alessio Stefani, Dr Md Rejvi Kaysir |
| Contact | jeremy.cohen@sydney.edu.au |
| Summary | The innovation at hand is a nanoparticle bioconjugate that employs a dual-nanoparticle approach to target and bind to both cancer cells and immune cells. |
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| Inventors | A/Professor Veysel Kayser, Mariam Tarkistani |
| Contact | julius.juarez@sydney.edu.au |
| Summary | Novel inhibitors that target the two-partner secretion system, potentially blocking the secretion of virulence factors in Gram-negative bacteria, offering a new approach to combat bacterial infections. |
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| Inventors | Matthew Thomas Doyle, Alfred Hartojo, Peggy Cotter, Richard Johnson |
| Contact | karmen.kong@sydney.edu.au |
| Summary | A new gene editing technology that offers enhanced precision and the capability to insert large DNA sequences without off-target mutations or triggering error-prone DNA repair. |
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| Inventors | Sandro F Ataide, Rezwan Siddiquee, Ruth Hall |
| Contact | karmen.kong@sydney.edu.au |
| Summary | This invention presents a new method forÌýassembling protein cages outside of cells, withoutÌýthe need for disassembly.ÌýTheÌýtechnology offers greater reliability, flexibility, andÌýconsistency compared to existing methods, as wellÌýas simplifying manufacturing processes, making itÌýwell-suited for applications in therapeutics, vaccines and more. |
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| Inventors | A/Prof Yu Heng Lau, Dr Taylor Szyszka and PhD candidate Rezwan Siddiquee |
| Contact | jeremy.cohen@sydney.edu.au |
| Summary | This technology chemically modifies polyhydroxyalkanoates by bonding them with polyamines to enhance their thermal, mechanical, and processing properties for advanced biomedical applications. Project details (PDF, 103KB) |
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| Inventors | Dr Sepehr Talebian, Chen Wang, Prof. Fariba Dehghani, A/Prof Sina Naficy |
| Contact | lulu.xue@sydney.edu.au |
| Summary | A novel Linear Maximum a Posteriori (LMAP) decoding method and decoder architecture for rate 1/2 convolutional codes that significantly reduces decoding complexity and delay while matching optimal MAP decoding performance. Project details (PDF, 99KB) |
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| Inventors | Prof Yonghui Li, Chentao Yue, Prof. Branka Vucetic |
| Contact | lulu.xue@sydney.edu.au |
| Summary | Innovative organic semiconductor nanoparticles designed to mimic human retinal photoreceptors for advanced retinal prosthetic applications. Project details (PDF, 99KB) |
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| Inventors | A/Professor Matthew Griffith, A/Professor Rebecca Lim |
| Contact | lulu.xue@sydney.edu.au |
| Summary | A technology that adds low cost and simple architecture to the existing advantages of photonics-based radar. |
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| Inventors | Dr Yang Liu, Mr Ziqian Zhang, Professor Benjamin Eggleton |
| Contact | jeremy.cohen@sydney.edu.au |
| Summary | An innovative method and system utilizing microbial enzyme-mediated hydrolysis combined with pre-treatment and post-treatment processes to efficiently recycle fibre-reinforced polymers into high-quality carbon and glass fibres. Project details (PDF, 99KB) |
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| Inventors | Dr Ali Hadigheh, Yaning Wei |
| Contact | lulu.xue@sydney.edu.au |
| Summary | An on-chip real-time versatile sensing system that can be applied to many in-situ and off-line measurement scenarios including electric vehicle battery monitoring, blood tests, and nanoparticles sensing. |
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| Inventors | Professor Xiaoke Yi, Dr Xiaoyi Tian |
| Contact | lulu.xue@sydney.edu.au |
| Summary | Fibre sensors made of this low YM material will improve existing uses of OFS technology and open new opportunities in smart textiles, wearables, implantable therapeutic devices, healthcare, and soft robotics. |
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| Inventors | Professor Simon Fleming, Dr Richard Lwin, Dr Alessio Stefani, Dr Md Rejvi Kaysir |
| Contact | jeremy.cohen@sydney.edu.au |
| Summary | An improved protein coating process that enables covalent attachment of any protein to a glass surface without using chemical linkers or any additional reagents, which could drive growth in the global medical coatings market. |
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| Inventors | Professor Marcela Bilek, Dr Clara Thao Hoang Tran, Dr Stuart Tallis Fraser, Dr Badwi Bob Boumelhem, Dr Aaron Gilmour |
| Contact | lulu.xue@sydney.edu.au |
| Summary | A revolutionary technology to help those grappling with complex communication needs. |
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| Inventors | Professor Alistair McEwan, Professor Petra Karlsson, Haifeng Zha |
| Contact | lulu.xue@sydney.edu.au |
| Summary | A compact wearable ECG monitoring device employing AI-based deep learning algorithms for accurate, real-time diagnosis of cardiac arrhythmia. |
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| Inventors | Professor Branka Vucetic, Associate Professor Zihuai Lin, Xucun Yan |
| Contact | lulu.xue@sydney.edu.au |
| Summary | A framework designed to support emergency nurses in assessing and managing emergency department patients after triage. |
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| Inventors | Belinda Kennedy, Julie Considine, Kate Curtis, John Mackenzie, Margaret Murphy, Sarah Kourouche, Margaret Fry, Ramon Shaban |
| Contact | karmen.kong@sydney.edu.au |
| Summary | AnÌýadaptation of the original HIRAID frameworkÌýfor residential aged care. Ìý |
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| Inventors | Professor Ramon Shaban, Dr Catherine Viengkham, Professor Kate Curtis AO, Professor Julie Considine AO (Deakin University), Professor Margaret Fry AM (UTS) |
| Contact | karmen.kong@sydney.edu.au |
| Summary | A custom-designed web-based platform for automating the administration of the Indigenous Tutorial Assistance Scheme-Tertiary Tuition (ITAS-TT). |
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| Creators | Designed at the University of Sydney by the Office of the DVC (Indigenous Strategy and Services) and developed by TechLab in Information and Communication Technology (ICT) |
| Contact | karmen.kong@sydney.edu.au |
| Summary | An online program that provides peerÌýsupportÌýtools, mental health literacy content andÌýhelpÌýseeking guidance for teenagers.Ìý |
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| Creators | DrÌýLouise White, Sophia Spallek,ÌýMsÌýAnÌýNguyen,ÌýMsÌýAinsleyÌýFurneaux‑Bate. |
| Contact | emma-louise.hunsley@sydney.edu.au |
| Summary |
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| Creators | Lee Wallace, Victoria Elizabeth Rawlings, Premeet Kaur Sidhu, Xavier Ho, Logan Timmins |
| Contact | karmen.kong@sydney.edu.au |
Commercialisation team
Our Commercialisation team is here to help you navigate licensing, collaboration and investment opportunities, so you can bring innovation to life.